Pyloric Channel Ulcer With Betazole-Fast Achlorhydria

Pyloric regurgitation and gastric ulcer.

Using a radiological test for pyloric regurgitation described by Capper, Airth, and Kilby (1966), it was confirmed that the pylorus is normally competent but incompetent in gastric ulcer and chronic alcoholic gastritis and often incompetent in chronic duodenal ulcer. The significance of pyloric regurgitation in the aetiology of gastric ulcer is discussed.

Aberrant pancreatic tissue causing gastric ulcer and pyloric obstruction.

A 5-year-old boy was admitted for recurrent episodies of upper abdominal pain and vomiting for the past two years associated with loss of weight. The vomiting was non projectile, occurred shortly after meals, and was never blood or bile stained. On examination there was visible gastric peristalsis and mildly enlarged liver. The cardiovascular system examination revealed a continuous murmur in t...

Anti-ulcer Activity of Withania Somnifera in Stress plus Pyloric Ligation Induced Gastric Ulcer in Rats

Anti-ulcer activity of methanolic extract of Withania somnifera (Ashwagandha) and its action against stress plus pyloric ligation induced gastric ulcer in rats has been reported. Treatment with Withania somnifera extract (100 mg/Kg/day p.o.) for 15 days significantly reduced ulcer index as compared to control group. Extract also significantly reduced volume of gastric secretion, free acidity an...

Achlorhydria by ezrin knockdown

Loss of gastric acid secretion is pathologically known as achlorhydria. Acid-secreting parietal cells are characterized by abundant expression of ezrin (Vil2), one of ezrin/radixin/moesin proteins, which generally cross-link actin filaments with plasma membrane proteins. Here, we show the direct in vivo involvement of ezrin in gastric acid secretion. Ezrin knockout (Vil2(-/-)) mice did not surv...

Achlorhydria and Anæmia